Bone-protective effects of bioactive fractions and ingredients in Sambucus williamsii HANCE

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Bone-protective effects of bioactive fractions and ingredients in Sambucus williamsii HANCE.

Our previous study demonstrated that 60 % ethanol crude extract of Sambucus williamsii HANCE (SWH) improved bone mass, bone strength and bone micro-structure in both ovariectomised (OVX) rats and mice. The present study aims to identify the bioactive fractions and ingredients in SWH that account for its osteoprotective effects. Bilateral sham-operated mice acted as controls. OVX C57BL/6J mice, ...

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Phytochemicals and potential health effects of Sambucus williamsii Hance (Jiegumu)

Sambucus williamsii Hance (Jiegumu) is traditionally used in Chinese medicine to treat bone and joint diseases. The major phytochemicals in S. williamsii are lignans, terpenoids, and phenolic acids, together with trace amounts of essential oils, minerals, amino acids, and natural pigments. In this review, a database search for studies published from 1990 to November 2015 was conducted using Pub...

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Bioactive lignan constituents from the twigs of Sambucus williamsii.

As part of our ongoing search for bioactive constituents of natural Korean medicinal plants, three new lignan derivatives, sambucasinol A-C (1-3), together with 7 known compounds (4-10) were isolated from the twigs of Sambucus williamsii. The structures of these new compounds were determined by a combination of 1D and 2D NMR spectroscopic data analysis, as well as circular dichroism (CD) spectr...

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Two new iridoid glycosides from the root barks of Sambucus williamsii Hance.

Two new iridoid glycosides, named williamsoside C (1) and williamsoside D (2) were isolated from the root barks of Sambucus williamsii Hance. Their structures were established on the basis of extensive spectroscopic analysis (1D, 2D NMR and HRESIMS) and chemical studies as α-D-glucopyranosyl (1→2)-β-D-fructofuranosyl (4→6)-β-morroniside (1) and 7β-O-ethyl morroniside-(6'-O-7'')-β-morroniside (2...

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ژورنال

عنوان ژورنال: British Journal of Nutrition

سال: 2011

ISSN: 0007-1145,1475-2662

DOI: 10.1017/s0007114511002546